Many people believe that eating arepas is less healthy than eating wheat flour-based bread, but both offer a similar caloric content and can be considered a part of a balanced diet. Corn, however, contains a gluten-free protein called Zein, which makes it much healthier for celiacs.

The arepa is a pre-Columbian dish from the area that is now Colombia, Panama and Venezuela. Instruments used to make flour for the arepas, and the clay slabs on which they were cooked, were often found at archaeological sites in the area.

Pupusas are larger and flatter than arepas and are made with masa harina rather than masarepa. Masa harina is a type of cornmeal made from corn that has been treated with lye or other alkaline solution to remove the hull and germ.